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Reduced Na(+) Affinity Increases Turnover of Salmonella enterica Serovar Typhimurium MelB

The melibiose permease of Salmonella enterica serovar Typhimurium (MelB(St)) catalyzes symport of melibiose with Na(+), Li(+), or H(+). Bioinformatics and mutational analyses indicate that a conserved Gly117 (helix IV) is a component of the Na(+)-binding site. In this study, Gly117 was mutated to Se...

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Autors principals: Jakkula, S. Vivek, Guan, Lan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458675/
https://ncbi.nlm.nih.gov/pubmed/22865849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01206-12
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