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Thermodynamic cooperativity of cosubstrate binding and cation selectivity of Salmonella typhimurium MelB

The Na(+)-coupled melibiose symporter MelB, which can also be coupled to H(+) or Li(+) transport, is a prototype for the glycoside-pentoside-hexuronide:cation symporter family. Although the 3-D x-ray crystal structure of Salmonella typhimurium MelB (MelB(St)) has been determined, the symport mechani...

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Vydáno v:J Gen Physiol
Hlavní autoři: Hariharan, Parameswaran, Guan, Lan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677108/
https://ncbi.nlm.nih.gov/pubmed/29054867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711788
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