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Determinants of the selective toxicity of alloxan to the pancreatic B cell.

The diabetogenic agent alloxan exerts a preferential cytotoxic effect on the pancreatic B cell. The determinants of such a tissue specificity were investigated. Alloxan accumulated rapidly in liver and pancreatic islets but much more slowly in muscle. The activity of glutathione peroxidase and the r...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Malaisse, W J, Malaisse-Lagae, F, Sener, A, Pipeleers, D G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1982
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC345866/
https://ncbi.nlm.nih.gov/pubmed/7038690
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