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The basic linker of macroH2A stabilizes DNA at the entry/exit site of the nucleosome

MacroH2A is a histone H2A variant that is typically found in heterochromatic regions of the genome. A positively charged linker that connects the histone-fold with the macro-domain was suggested to have DNA-binding properties, and has been shown to promote oligomerization of chromatin fibers. Here w...

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Detalhes bibliográficos
Main Authors: Chakravarthy, Srinivas, Patel, Ashok, Bowman, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458575/
https://ncbi.nlm.nih.gov/pubmed/22753032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks645
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