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The conformational state of the nucleosome entry–exit site modulates TATA box-specific TBP binding

The TATA binding protein (TBP) is a critical transcription factor used for nucleating assembly of the RNA polymerase II machinery. TBP binds TATA box elements with high affinity and kinetic stability and in vivo is correlated with high levels of transcription activation. However, since most promoter...

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Detalhes bibliográficos
Main Authors: Hieb, Aaron R., Gansen, Alexander, Böhm, Vera, Langowski, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081063/
https://ncbi.nlm.nih.gov/pubmed/24829456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku423
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