Загрузка...
TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1
The abortive activity of topoisomerases can result in clastogenic and/or lethal DNA damage in which the topoisomerase is covalently linked to the 3′- or 5′-terminus of a DNA strand break. This type of DNA damage is implicated in chromosome translocations and neurological disease and underlies the cl...
Сохранить в:
| Главные авторы: | , , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2012
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458563/ https://ncbi.nlm.nih.gov/pubmed/22740648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks622 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|