A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis

Streptomyces davawensis is the only organism known to synthesize the antibiotic roseoflavin, a riboflavin (vitamin B(2)) analog. Roseoflavin is converted to roseoflavin mononucleotide (RoFMN) and roseoflavin adenine dinucleotide in the cytoplasm of target cells. (Ribo-)Flavin mononucleotide (FMN) ri...

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Detalhes bibliográficos
Main Authors: Pedrolli, Danielle Biscaro, Matern, Andreas, Wang, Joy, Ester, Miriam, Siedler, Kathrin, Breaker, Ronald, Mack, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458559/
https://ncbi.nlm.nih.gov/pubmed/22740651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks616
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