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The Bifunctional Flavokinase/Flavin Adenine Dinucleotide Synthetase from Streptomyces davawensis Produces Inactive Flavin Cofactors and Is Not Involved in Resistance to the Antibiotic Roseoflavin

Streptomyces davawensis synthesizes the antibiotic roseoflavin, one of the few known natural riboflavin analogs, and is roseoflavin resistant. It is thought that the endogenous flavokinase (EC 2.7.1.26)/flavin adenine dinucleotide (FAD) synthetase (EC 2.7.7.2) activities of roseoflavin-sensitive org...

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Detalhes bibliográficos
Main Authors: Grill, Simon, Busenbender, Simone, Pfeiffer, Matthias, Köhler, Uwe, Mack, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258686/
https://ncbi.nlm.nih.gov/pubmed/18156273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01586-07
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