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Chronic low-dose ultraviolet-induced mutagenesis in nucleotide excision repair-deficient cells

UV radiation induces two major types of DNA lesions, cyclobutane pyrimidine dimers (CPDs) and 6-4 pyrimidine–pyrimidine photoproducts, which are both primarily repaired by nucleotide excision repair (NER). Here, we investigated how chronic low-dose UV (CLUV)-induced mutagenesis occurs in rad14Δ NER-...

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Bibliografiske detaljer
Main Authors: Haruta, Nami, Kubota, Yoshino, Hishida, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458537/
https://ncbi.nlm.nih.gov/pubmed/22743272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks580
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