Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia

The transcription factor encoded by the E-twenty-six (ETS)-related gene, ERG, is an essential regulator of hematopoietic stem cell function and a potent human oncoprotein. Enforced expression of ERG in murine hematopoietic cells leads to the development of a well-characterized lymphoid leukemia and...

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Bibliographische Detailangaben
Hauptverfasser: Carmichael, Catherine L., Metcalf, Donald, Henley, Katya J., Kruse, Elizabeth A., Di Rago, Ladina, Mifsud, Sandra, Alexander, Warren S., Kile, Benjamin T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458381/
https://ncbi.nlm.nih.gov/pubmed/22936051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213454109
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