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Protonation state of E71 in KcsA and its role for channel collapse and inactivation

The prototypical prokaryotic potassium channel KcsA alters its pore depending on the ambient potassium; at high potassium, it exists in a conductive form, and at low potassium, it collapses into a nonconductive structure with reduced ion occupancy. We present solid-state NMR studies of KcsA in which...

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Bibliographische Detailangaben
Hauptverfasser: Bhate, Manasi P., McDermott, Ann E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458351/
https://ncbi.nlm.nih.gov/pubmed/22942391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211900109
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