Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids.

Arachidonic acid is oxidized by a NADPH-dependent oxygenase of rat liver microsomes to a number of oxygen-containing products, which can be resolved by HPLC. Several of these products have been purified and characterized. They exhibit an absorbance in the UV region of the spectrum that has a maximum...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Capdevila, J, Marnett, L J, Chacos, N, Prough, R A, Estabrook, R W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1982
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6801662/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.3.767
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