Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids.
Arachidonic acid is oxidized by a NADPH-dependent oxygenase of rat liver microsomes to a number of oxygen-containing products, which can be resolved by HPLC. Several of these products have been purified and characterized. They exhibit an absorbance in the UV region of the spectrum that has a maximum...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1982
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6801662/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.3.767 |
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