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Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics

Aberrant mitochondrial function, morphology, and transport are main features of neurodegenerative diseases. To date, mitochondrial transport within neurons is thought to rely mainly on microtubules, whereas actin might mediate short-range movements and mitochondrial anchoring. Here, we analyzed the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beck, Henning, Flynn, Kevin, Lindenberg, Katrin S., Schwarz, Heinz, Bradke, Frank, Di Giovanni, Simone, Knöll, Bernd
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458318/
https://ncbi.nlm.nih.gov/pubmed/22927399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208141109
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