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Opioids regulate cGMP formation in cloned neuroblastoma cells

Opioid agonists caused a rapid dose-related elevation of the cGMP content of N4TG1 murine neuroblastoma cells. An excellent correlation was found between the rank order of potency of agonists in stimulating cGMP accumulation and in displacing [(3)H]etorphine ([(3)H]ETP) bound to intact cells. The na...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Gwynn, Germaine J., Costa, Erminio
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1982
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16593149/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.2.690
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