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Opioids regulate cGMP formation in cloned neuroblastoma cells

Opioid agonists caused a rapid dose-related elevation of the cGMP content of N4TG1 murine neuroblastoma cells. An excellent correlation was found between the rank order of potency of agonists in stimulating cGMP accumulation and in displacing [(3)H]etorphine ([(3)H]ETP) bound to intact cells. The na...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Gwynn, Germaine J., Costa, Erminio
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16593149/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.2.690
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