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Evidence for Water-Tuned Structural Differences in Proteins: An Approach Emphasizing Variations in Local Hydrophilicity

We present experimental evidence for the significant effect that water can have on the functional structure of proteins in solution. Human (HSA) and Bovine Serum Albumin (BSA) have an amino acid sequence identity of 75.52% and are chosen as model proteins. We employ EPR-based nanoscale distance meas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Akdogan, Yasar, Reichenwallner, Jörg, Hinderberger, Dariush
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458090/
https://ncbi.nlm.nih.gov/pubmed/23049837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045681
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