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IL-27-Induced Gene Expression Is Downregulated in HIV-Infected Subjects

OBJECTIVE: To characterize the effect of HIV infection on IL-27-induced gene expression. DESIGN: During HIV infection, cytokine expression and function become deregulated. IL-27 is an important modulator of inflammatory responses. Interestingly, IL-27 can inhibit HIV replication in T cells and monoc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guzzo, Christina, Hopman, Wilma M., Che Mat, Nor Fazila, Wobeser, Wendy, Gee, Katrina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458084/
https://ncbi.nlm.nih.gov/pubmed/23049843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045706
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