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Tie2-Dependent Neovascularization of the Ischemic Hindlimb Is Mediated by Angiopoietin-2
The angiopoietins (ANGPT) are ligands for the endothelial cell (EC) receptor tyrosine kinase, Tie2. Angpt-1 is a Tie2 agonist that promotes vascular maturation and stabilization, whereas Angpt-2 is a partial agonist/antagonist involved in the initiation of postnatal angiogenesis. Therefore, we hypot...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458045/ https://ncbi.nlm.nih.gov/pubmed/23049737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043568 |
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