Activation of Protease-Activated Receptor 2 Induces VEGF Independently of HIF-1

BACKGROUND: Human adipose stem cells (hASCs) can promote angiogenesis through secretion of proangiogenic factors such as vascular endothelial growth factor (VEGF). In other cell types, it has been shown that induction of VEGF is mediated by both protease activated receptor 2 (PAR2) and hypoxia induc...

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Bibliografiske detaljer
Main Authors: Rasmussen, Jeppe Grøndahl, Riis, Simone Elkjær, Frøbert, Ole, Yang, Sufang, Kastrup, Jens, Zachar, Vladimir, Simonsen, Ulf, Fink, Trine
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457954/
https://ncbi.nlm.nih.gov/pubmed/23049945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046087
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