Allelic exclusion of immunoglobulin expression is not caused by somatic segregation

We have investigated the karyotype of immunoglobulin-producing cells in heterozygous animals. Using a karyotypic marker for one homolog of a chromosome carrying immunoglobulin genes, we established that immunoglobulin-producing cells are heterozygous with respect to this chromosome. Therefore, allel...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Wabl, Matthias R., Tenkhoff, Maria
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1982
Schlagworte:	Biological Sciences: Immunology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345794/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6952212/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.2.606
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