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Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice

Adipose tissue macrophages are important mediators of inflammation and insulin resistance in obesity. IFN-γ is a central regulator of macrophage function. The role of IFN-γ in regulating systemic inflammation and insulin resistance in obesity is unknown. We studied obese IFN-γ knockout mice to ident...

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Detalhes bibliográficos
Main Authors: O’Rourke, Robert W., White, Ashley E., Metcalf, Monja D., Winters, Brian R., Diggs, Brian S., Zhu, Xinxia, Marks, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457921/
https://ncbi.nlm.nih.gov/pubmed/22386937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2012.01.018
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