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A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population
BACKGROUND: The human ATP-binding cassette, subfamily B, member 11 (ABCB11) gene encodes the bile salt export pump, which is exclusively expressed at the canalicular membrane of hepatocytes. A frequent variant in the coding region, c.1331 T > C, leading to the amino acid exchange p.V444A, has bee...
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Glavni autori: | , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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BioMed Central
2012
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457846/ https://ncbi.nlm.nih.gov/pubmed/22681771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-12-63 |
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