A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population

BACKGROUND: The human ATP-binding cassette, subfamily B, member 11 (ABCB11) gene encodes the bile salt export pump, which is exclusively expressed at the canalicular membrane of hepatocytes. A frequent variant in the coding region, c.1331 T > C, leading to the amino acid exchange p.V444A, has bee...

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Autores principales: Müllenbach, Roman, Weber, Susanne N, Krawczyk, Marcin, Zimmer, Vincent, Sarrazin, Christoph, Lammert, Frank, Grünhage, Frank
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457846/
https://ncbi.nlm.nih.gov/pubmed/22681771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-12-63
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