A phase I/IIA study of AGS-PSCA for castration-resistant prostate cancer

BACKGROUND: This first-in-human phase I/IIA study was designed to evaluate the safety and pharmacokinetics (PKs) of AGS-PSCA a fully human monoclonal antibody directed to prostate stem cell antigen (PSCA) in progressive castration-resistant prostate cancer. PATIENTS AND METHODS: Twenty-nine patients...

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Bibliographic Details
Main Authors: Morris, M. J., Eisenberger, M. A., Pili, R., Denmeade, S. R., Rathkopf, D., Slovin, S. F., Farrelly, J., Chudow, J. J., Vincent, M., Scher, H. I., Carducci, M. A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457748/
https://ncbi.nlm.nih.gov/pubmed/22553195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mds078
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