Inhibition of HIV Replication by Cyclic and Hairpin PNAs Targeting the HIV-1 TAR RNA Loop

Human immunodeficiency virus-1 (HIV-1) replication and gene expression entails specific interaction of the viral protein Tat with its transactivation responsive element (TAR), to form a highly stable stem-bulge-loop structure. Previously, we described triphenylphosphonium (TPP) cation-based vectors...

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Autors principals: Upert, Gregory, Di Giorgio, Audrey, Upadhyay, Alok, Manvar, Dinesh, Pandey, Nootan, Pandey, Virendra N., Patino, Nadia
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457641/
https://ncbi.nlm.nih.gov/pubmed/23029603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/591025
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