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Prevalence and specificity of LKB1 genetic alterations in lung cancers
Germline LKB1 mutations cause Peutz–Jeghers syndrome, a hereditary disorder that predisposes to gastrointestinal hamartomatous polyposis and several types of malignant tumors. Somatic LKB1 alterations are rare in sporadic cancers, however, a few reports showed the presence of somatic alterations in...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457639/ https://ncbi.nlm.nih.gov/pubmed/17384680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210418 |
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