Alleviation of Neuropathic Pain Hypersensitivity by Inhibiting Neuronal Pentraxin 1 in the Rostral Ventromedial Medulla

Peripheral nerve injury causes spontaneous and long-lasting pain, hyperalgesia, and allodynia. Excitatory amino acid receptor-dependent increases in descending facilitatory drive from the brainstem rostral ventromedial medulla (RVM) contribute to injury-evoked hypersensitivity. Although increased ex...

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Bibliographic Details
Main Authors: Zapata, Agustin, Pontis, Silvia, Schepers, Raf J., Wang, Ruizhong, Oh, Eric, Stein, Alexandra, Bäckman, Cristina M., Worley, Paul, Enguita, Marta, Abad, M. Alba, Trullas, Ramon, Shippenberg, Toni S.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2012
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Brief Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457630/
https://ncbi.nlm.nih.gov/pubmed/22956834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2730-12.2012
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