Erythropoietin for Neuroprotection in Neonatal Encephalopathy: Safety and Pharmacokinetics

OBJECTIVE: To determine the safety and pharmacokinetics of erythropoietin (Epo) given in conjunction with hypothermia for hypoxic-ischemic encephalopathy (HIE). We hypothesized that high dose Epo would produce plasma concentrations that are neuroprotective in animal studies (ie, maximum concentratio...

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Auteurs principaux: Wu, Yvonne W., Bauer, Larry A., Ballard, Roberta A., Ferriero, Donna M., Glidden, David V., Mayock, Dennis E., Chang, Taeun, Durand, David J., Song, Dongli, Bonifacio, Sonia L., Gonzalez, Fernando F., Glass, Hannah C., Juul, Sandra E.
Format: Artigo
Langue:Inglês
Publié: American Academy of Pediatrics 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457622/
https://ncbi.nlm.nih.gov/pubmed/23008465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1542/peds.2012-0498
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