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Crystal Structure and Functional Analysis of JMJD5 Indicate an Alternate Specificity and Function
JMJD5 is a Jumonji C (JmjC) protein that has been implicated in breast cancer tumorigenesis, circadian rhythm regulation, embryological development, and osteoclastogenesis. Recently, JMJD5 (also called KDM8) has been reported to demethylate dimethylated Lys-36 in histone H3 (H3K36me2), regulating ge...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457536/ https://ncbi.nlm.nih.gov/pubmed/22851697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00513-12 |
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