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Crystal structure of homoisocitrate dehydrogenase from Schizosaccharomyces pombe
Homoisocitrate dehydrogenase (HICDH) catalyzes the conversion of homoisocitrate to 2-oxoadipate, the third enzymatic step in the α-aminoadipate pathway by which lysine is synthesized in fungi and certain archaebacteria. This enzyme represents a potential target for anti-fungal drug design. Here, we...
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| Publicado no: | Proteins |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332711/ https://ncbi.nlm.nih.gov/pubmed/22105743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23231 |
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