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Population Pharmacokinetics of Conventional and Intermittent Dosing of Liposomal Amphotericin B in Adults: a First Critical Step for Rational Design of Innovative Regimens

There is increased interest in intermittent regimen of liposomal amphotericin B, which may facilitate use in ambulatory settings. Little is known, however, about the most appropriate dosage and schedule of administration. Plasma pharmacokinetic data were acquired from 30 patients receiving liposomal...

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Detalhes bibliográficos
Main Authors: Hope, William W., Goodwin, Joanne, Felton, Timothy W., Ellis, Michael, Stevens, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457383/
https://ncbi.nlm.nih.gov/pubmed/22869566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00933-12
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