FoxO-Dependent Regulation of Diacylglycerol Kinase α Gene Expression

Diacylglycerol kinase α (DGKα) regulates diacylglycerol levels, catalyzing its conversion into phosphatidic acid. The α isoform is central to immune response regulation; it downmodulates Ras-dependent pathways and is necessary for establishment of the unresponsive state termed anergy. DGKα functions...

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Autori principali: Martínez-Moreno, Mónica, García-Liévana, Job, Soutar, Denise, Torres-Ayuso, Pedro, Andrada, Elena, Zhong, Xiao-Ping, Koretzky, Gary A., Mérida, Isabel, Ávila-Flores, Antonia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457341/
https://ncbi.nlm.nih.gov/pubmed/22890845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00654-12
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