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Disruption of the Selenocysteine Lyase-Mediated Selenium Recycling Pathway Leads to Metabolic Syndrome in Mice

Selenium (Se) is an essential trace element used for biosynthesis of selenoproteins and is acquired either through diet or cellular recycling mechanisms. Selenocysteine lyase (Scly) is the enzyme that supplies Se for selenoprotein biosynthesis via decomposition of the amino acid selenocysteine (Sec)...

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Main Authors: Seale, Lucia A., Hashimoto, Ann C., Kurokawa, Suguru, Gilman, Christy L., Seyedali, Ali, Bellinger, Frederick P., Raman, Arjun V., Berry, Marla J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457337/
https://ncbi.nlm.nih.gov/pubmed/22890841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00293-12
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