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Construction of a Gammaretrovirus with a Novel Tropism and Wild-Type Replication Kinetics Capable of Using Human APJ as Entry Receptor

We have constructed a replication-competent gammaretrovirus (SL3-AP) capable of using the human G-protein-coupled receptor hAPJ as its entry receptor. The envelope protein of the virus was made by insertion of the 13-amino-acid peptide ligand for hAPJ, flanked by linker sequences, into one of the va...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bahrami, Shervin, Pagh, Kristina, Ejegod, Ditte, Duch, Mogens, Tolstrup, Martin, Pedersen, Finn Skou
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457326/
https://ncbi.nlm.nih.gov/pubmed/22811542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01028-12
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