Coupling of receptor interference and a host-dependent post-binding entry deficiency in a gammaretroviral envelope protein

BACKGROUND: SL3-2 is a unique polytropic murine gammaretroviral isolate that is only able to infect murine cells. We have previously shown that two mutations R212G and T213I located on the surface of the receptor binding domain in a region designated the VR3 loop can alter the species tropism of thi...

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Hlavní autoři: Bahrami, Shervin, Ejegod, Ditte, Sørensen, Karina Dalsgaard, Pedersen, Finn Skou
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827363/
https://ncbi.nlm.nih.gov/pubmed/20137084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-9
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