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NS1-Truncated Live Attenuated Virus Vaccine Provides Robust Protection to Aged Mice from Viral Challenge

Immunological changes associated with age contribute to the high rates of influenza virus morbidity and mortality in the elderly. Compounding this problem, aged individuals do not respond to vaccination as well as younger, healthy adults. Efforts to increase protection to this demographic group are...

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Detalles Bibliográficos
Main Authors: Pica, Natalie, Langlois, Ryan A., Krammer, Florian, Margine, Irina, Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457311/
https://ncbi.nlm.nih.gov/pubmed/22787224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01131-12
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