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Imiquimod Suppresses Propagation of Herpes Simplex Virus 1 by Upregulation of Cystatin A via the Adenosine Receptor A(1) Pathway

Imiquimod is recognized as an agonist for Toll-like receptor 7 (TLR7) in immunocompetent cells. TLR7, as well as TLR3 and TLR8, triggers the immune responses, such as the production of type I interferons (IFNs) and proinflammatory cytokines via recognition of viral nucleic acids in the infected cell...

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Detalhes bibliográficos
Main Authors: Kan, Yuji, Okabayashi, Tamaki, Yokota, Shin-ichi, Yamamoto, Soh, Fujii, Nobuhiro, Yamashita, Toshiharu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457300/
https://ncbi.nlm.nih.gov/pubmed/22787201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01196-12
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