Optimum Length and Flexibility of Reovirus Attachment Protein σ1 Are Required for Efficient Viral Infection

Reovirus attachment protein σ1 is an elongated trimer with head-and-tail morphology that engages cell-surface carbohydrate and junctional adhesion molecule A (JAM-A). The σ1 protein is comprised of three domains partitioned by two flexible linkers termed interdomain regions (IDRs). To determine the...

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Main Authors: Bokiej, Magdalena, Ogden, Kristen M., Ikizler, Mine, Reiter, Dirk M., Stehle, Thilo, Dermody, Terence S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457286/
https://ncbi.nlm.nih.gov/pubmed/22811534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01338-12
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