Reverse Genetics Recovery of Lujo Virus and Role of Virus RNA Secondary Structures in Efficient Virus Growth

Arenaviruses are rodent-borne viruses with a bisegmented RNA genome. A genetically unique arenavirus, Lujo virus, was recently discovered as the causal agent of a nosocomial outbreak of acute febrile illness with hemorrhagic manifestations in Zambia and South Africa. The outbreak had a case fatality...

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Detalhes bibliográficos
Main Authors: Bergeron, Éric, Chakrabarti, Ayan K., Bird, Brian H., Dodd, Kim A., McMullan, Laura K., Spiropoulou, Christina F., Nichol, Stuart T., Albariño, César G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457263/
https://ncbi.nlm.nih.gov/pubmed/22837210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01144-12
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