Hepatitis C Virus Induces Epidermal Growth Factor Receptor Activation via CD81 Binding for Viral Internalization and Entry

While epidermal growth factor receptor (EGFR) has been shown to be important in the entry process for multiple viruses, including hepatitis C virus (HCV), the molecular mechanisms by which EGFR facilitates HCV entry are not well understood. Using the infectious cell culture HCV model (HCVcc), we dem...

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Detalhes bibliográficos
Main Authors: Diao, Jingyu, Pantua, Homer, Ngu, Hai, Komuves, Laszlo, Diehl, Lauri, Schaefer, Gabriele, Kapadia, Sharookh B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457153/
https://ncbi.nlm.nih.gov/pubmed/22855500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00750-12
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