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Second-Site Mutations Selected in Transcriptional Regulatory Sequences Compensate for Engineered Mutations in the Vesicular Stomatitis Virus Nucleocapsid Protein

The active template for RNA synthesis for vesicular stomatitis virus (VSV) and other negative-strand viruses is the RNA genome in association with the nucleocapsid (N) protein. The N protein molecules sequester the genomic RNA and are linked together by a network of noncovalent interactions. We prev...

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Bibliografiske detaljer
Main Authors: Harouaka, Djamila, Wertz, Gail W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457138/
https://ncbi.nlm.nih.gov/pubmed/22875970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01238-12
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