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Mutations in the C-Terminal Loop of the Nucleocapsid Protein Affect Vesicular Stomatitis Virus RNA Replication and Transcription Differentially

The 2.9-Å structure of the vesicular stomatitis virus nucleocapsid (N) protein bound to RNA shows the RNA to be tightly sequestered between the two lobes of the N protein. Domain movement of the lobes of the N protein has been postulated to facilitate polymerase access to the RNA template. We invest...

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Библиографические подробности
Главные авторы: Harouaka, Djamila, Wertz, Gail W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772671/
https://ncbi.nlm.nih.gov/pubmed/19726519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00813-09
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