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Impairment of Interrelated Iron- and Copper Homeostatic Mechanisms in Brain Contributes to the Pathogenesis of Neurodegenerative Disorders

Iron and copper are important co-factors for a number of enzymes in the brain, including enzymes involved in neurotransmitter synthesis and myelin formation. Both shortage and an excess of iron or copper will affect the brain. The transport of iron and copper into the brain from the circulation is s...

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Main Authors: Skjørringe, Tina, Møller, Lisbeth Birk, Moos, Torben
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Research Foundation 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3456798/
https://ncbi.nlm.nih.gov/pubmed/23055972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00169
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