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Chaperonin-Affected Folding of Globular Proteins

We studied the effect of GroEL on the kinetic refolding ofα-lactalbumin by stopped-flow fluorescence techniques. We usedwild-type GroEL and its ATPase-defficient mutant D398A, and studied thebinding constants between GroEL and the molten globule foldingintermediate at various concentrations of ADP a...

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Détails bibliographiques
Auteurs principaux: Kuwajima, K., Makio, T., Inobe, T.
Format: Artigo
Langue:Inglês
Publié: Kluwer Academic Publishers 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3456655/
https://ncbi.nlm.nih.gov/pubmed/23345759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1019993102869
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