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Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.

Incubation of turkey erythrocytes with the phorbol ester phorbol 12-myristate 13-acetate (PMA) results in a dose- and time-dependent desensitization of isoproterenol-stimulated adenylate cyclase activity. Compared to controls, membranes from PMA-treated cells have an isoproterenol-stimulated adenyla...

詳細記述

保存先:
書誌詳細
主要な著者: Kelleher, D J, Pessin, J E, Ruoho, A E, Johnson, G L
フォーマット: Artigo
言語:Inglês
出版事項: 1984
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC345579/
https://ncbi.nlm.nih.gov/pubmed/6087317
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