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Accuracy of Preimplantation Diagnosis of Single-Gene Disorders by Polar Body Analysis of Oocytes
Purpose:A number of pitfalls in single-cell DNA analysis, including undetected DNA contamination, undetected allele drop out, and preferential amplification, may lead to misdiagnosis in preimplantation genetic diagnosis of single-gene disorders. Methods:Preimplantation genetic diagnosis was performe...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Kluwer Academic Publishers-Plenum Publishers
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3455765/ https://ncbi.nlm.nih.gov/pubmed/10224562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1020312823155 |
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