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Activation of the JC virus Tat-responsive transcriptional control element by association of the Tat protein of human immunodeficiency virus 1 with cellular protein Purα

JC virus is activated to replicate in glial cells of many AIDS patients with neurological disorders. In human glial cells, the human immunodeficiency virus 1 (HIV-1) Tat protein activates the major late promoter of JC virus through a Tat-responsive DNA element, termed upTAR, which is a recognition s...

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Autors principals: Krachmarov, Chavdar P., Chepenik, Lara G., Barr-Vagell, Sharon, Khalili, Kamel, Johnson, Edward M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC34556/
https://ncbi.nlm.nih.gov/pubmed/8943069
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