Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin.

Cultured human endothelial cells produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine; PAF) when stimulated with human thrombin. The response to thrombin is dose dependent, with a half-maximal effect at 0.17 unit/ml. The product is identified as PAF by the incorporation o...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Prescott, S M, Zimmerman, G A, McIntyre, T M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6587368/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.11.3534
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