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Modulation of inflammatory platelet-activating factor (PAF) receptor by the acyl analogue of PAF

Platelet-activating factor (PAF) is a potent inflammatory mediator that exerts its actions via the single PAF receptor (PAF-R). Cells that biosynthesize alkyl-PAF also make abundant amounts of the less potent PAF analogue acyl-PAF, which competes for PAF-R. Both PAF species are degraded by the plasm...

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Principais autores: Vyala Hanumanthareddy Chaithra, Shancy Petsel Jacob, Chikkamenahalli Lakshminarayana Lakshmikanth, Mosale Seetharam Sumanth, Kandahalli Venkataranganayaka Abhilasha, Chu-Huang Chen, Anita Thyagarajan, Ravi P. Sahu, Jeffery Bryant Travers, Thomas M. McIntyre, Kempaiah Kemparaju, Gopal Kedihithlu Marathe
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018-11-01
coleção:Journal of Lipid Research
Assuntos:
PAF analogue
PAF acetylhydrolase
platelet aggregation
PAF-like lipids
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S002222752030907X
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